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Titel på arbejdetUncemented Total Hip Arthroplasty. Femoral bone and implant interaction evaluated by Radiostereometric Analysis and Dual-Energy X-ray Absorptiometry
NavnKaren Dyreborg
Afdeling / StedRigshospitalet / Herlev-Gentofte Hospital
UniversitetUniversity of Copenhagen
  • Hip and knee surgery
Abstract / Summary

It is estimated that one in four people will develop symptomatic hip osteoarthritis before the age of 85. Total hip arthroplasty (THA) is the treatment for painful osteoarthritis of the hip and THA was in 2007 called out to be the operation of the century. This announcement was made because THA is a life-changing procedure. But, even though it is a surgical procedure with satisfying results for most of the patients, the need for implants with increased longevity and better function is still an issue, since patients undergoing this procedure now demand more than just pain relief. They want a new hip enabling them to continue their active lifestyle with golf, hiking and swimming.
In the studies I and II presented in this thesis, we evaluate the uncemented THA femoral components Echo Bi-Metric (EBM) and Bi-Metric (BM). This evaluation was found relevant because the BM has been on the market for >30 years with satisfying results; The EBM is the successor of the BM, made with a design based on the BM design but with theoretical enhancements. The EBM was introduced in 2007, and to our knowledge, no randomized controlled trial (RCT) has been made to evaluate this stem. Consequently, we designed and completed an investigator-initiated RCT with 62 patients (age-2.5, which is the threshold for osteoporosis.

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Paper 1

Primary supervisor:
Michael Mørk Petersen, MD, DMSc, Professor
Department of Orthopaedic Surgery, Rigshospitalet, Copenhagen, Denmark

Primary co-supervisor:
Søren Solgaard, MD, DMSc
Department of Orthopaedic Surgery, Herlev-Gentofte Hospital, Hellerup, Denmark

Gunnar Flivik, MD, PhD, Associate Professor
Department of Orthopaedics, Skåne University Hospital, Lund University, Lund, Sweden
Nikolaj Winther, MD, PhD, Associate Professor
Department of Orthopaedic Surgery, Rigshospitalet, Copenhagen, Denmark

Christian Skovgaard Nielsen, MD, PhD, Associate Professor
Department of Orthopaedics, Copenhagen University Hospital, Hvidovre, Denmark
Assessor representing Danish research:
Mogens Laursen, MD, PhD, Associate Professor
Orthopaedic Surgery Research Unit, Aalborg University Hospital, Aalborg, Denmark
Assessor from abroad:
Lars Nordsletten, MD, PhD, Professor
Orthopaedic Surgery, Oslo University Hospital, Oslo, Norway