Session 8: Pediatrics
Torsdag den 24. oktober
13:30 – 15:00
lokale: Helsinki/Oslo
Chairmen: Martin Gottliebsen / Keld Daubjerg
72. Is Radio Freqency Ablation (RFA) Epiphysiodesis Safe for Joint Articular Cartilage?
Juan Manuel Shiguetomi-Medina, Ahmed Abood, Ole Rahbek, Hans Stødkilde-Jørgensen, Bjarne Møller-Madsen
Department of Children's Orthopaedics / Orthopaedics Research Laboratory, Aarhus University Hospital; Orthopaedics Research Laboratory, Aarhus University Hospital; Departiment of Children's Orthopaedics, Aarhus University Hospital; The MR Research Center, Aarhus University Hospital; Departmen of Children's Orthopaedics, Aarhus University Hospital
Background: Epiphysiodesis made with RFA has resulted,
in animal models, an effective procedure that
disrupts the growth plate and induces LLD.
This procedure involves an increase of
temperature (>92°C) of the targeted region
causing thermal damage. To our knowledge,
no study that investigates the effect of this
procedure in the adjacent joint articular
cartilage has been reported
Purpose / Aim of Study: Proof of concept that epiphysiodesis made
with RFA is a safe procedure that disrupts
the growth plate without damaging the
adjacent joint articular cartilage
Materials and Methods: RFA Epiphysiodesis RFA was done for 8
minutes in vivo in 40 growing pig tibia physis.
In addition, three tibiae were ablated for 16
minutes, and three more for 24 minutes. As
a damage reference, 6 tibiae were ablated
on the joint articular cartilage for 8 minutes.
MRI was done ex vivo after the procedure to
evaluate the joint articular cartilage in all
samples using T1-weighted, T2-weighted
and water content sequences under a 1.5 T
magnetic field
Findings / Results: The intentionally-damaged articular cartilage
showed intensity changes on the MR. This
images were used as reference for damage.
We found no evidence of articular cartilage
damage on the 40 8 mins procedures. The
tibiae ablated for 16 mins showed a larger
lesion on the physis but the articular joint
cartilage was intact. No articular cartilage
damage was found on the tibiae ablated for
16 mins
Conclusions: Epiphysiodesis using RFA is safe for the
adjacent articular joint cartilage. This
study resembles possible results of RFA
epiphysiodesis on humans. Previous
studies suggest that an 8 min ablation is
enough to disrupt the growth plate. This
study shows that RFA can be done
safely in the growing physis even on
triple-long procedures. It is important to
highlight that all this evidence was
obtained on an animal model
73. Acetabular index 6 months after reduction of late presenting hip luxation predicts risk of secondary surgery for residual dysplasia of the hip
Louise Klingenberg, Klaus Hindsø, PhD, Andreas Balslev-Clausen
Orthopedic Department, Rigshospitalet
Background: Persistent dysplasia in developmental
dysplasia of the hip leads to early
osteoarthritis in the adult. Secondary
procedures may therefore be
necessary to correct residual dysplasia
after initial treatment for late presenting
hip dislocation. Timing of secondary
procedures can be difficult as some
hips normalize spontaneously
Purpose / Aim of Study: To identify early prognostic
radiografical markers for residual
dysplasia
Materials and Methods: A consecutive series of 60 patients
with late presenting hip dislocation
treated with reduction under
anesthesia from 2002 to 2005 were
identified in the hospital database (GS-
open). Patients with neuromuscular
dislocations or septic arthritis (8) or
insufficient radiological records (5)
were excluded leaving 47 children and
52 hips in the study group. X-rays were
evaluated with respect to acetabular
index (AI), center-edge-angle (CEA),
Shentons line and the sharpness of the
lateral corner.
Findings / Results: There were 37 closed and 15 open
reductions at a mean age of 16.5
months. 22 hips had secondary
procedures at an average age of 55
months. The procedures were proximal
femoral osteotomy(3), Salter osteotomy
(15) and combined Salter and femoral
osteotomies (4).
The AI-index declined from 38.1
postreduction to 17.1 at final follow up.
At six months after initial reduction
AI>35 degrees equaled a relative risk
of 2.8 (95.5%CI 1.6-4.8) for secondary
procedures. All hips with AI>40 had
secondary procedures whereas one
hip with an AI<30 had a secondary
procedure.
CEA, Shentons line and quality of the
lateral corner did not correlate to
secondary procedures at 6 months.
Conclusions: If the AI does not show significant
improvement within six months after
primary reduction, the need for
secondary procedures are very likely
and may be performed at an early
stage to improve hip function and
avoid residual dysplasia.
74. Identification of non-accidential injury in children in a Danish Emergency Room
Helen Latifi, Bodil Moltesen, Christian Wong
Almen Praksis introlæge, Region Hovedstaden; Pædiatrisk afd., Herlev Hospital; Ortopædkirugisk afd., Hvidovre Hospital
Background: Internationally, a high percentage of
children with non-accidental injuries
(NAI) are treated in the emergency
room (ER) not detected. NAI is found
to be connected with severe physical-
and psychological health
consequences, and can even be fatal
in some cases.
Purpose / Aim of Study: In this study we wanted to examine
whether Danish physicians in an ER
setting can identify and document NAI
adequately.
Materials and Methods: This study was a retrospective review
of all ER charts from Glostrup Hospital
from May 2009. All children from 0-3
years of age with treated injuries were
included. A new score system was
developed to assess the history
documentation (HD) sufficiency; with
this system, we were able to evaluate
to which extent the HD included the 6
relevant HD variables necessary to
rule out potential NAI: The place of
accident, time of accident, context of
injury, presence of witnesses,
mechanism of injury (MI) and the
accompanying caregiver.
Findings / Results: A total of 155 ER charts fulfilled the
inclusion criteria. The results showed
that 85 % documented the place of
accident, the time of accident in 97 %,
the context of injury in 20%, the
presence of witnesses in 7 % and the
accompanying caregiver in 35 % of the
ER charts.
The MI was adequately documented in
25%, partially documented in 31% and
undocumented in 44% of the ER
charts. The overall HD score used to
assess whether or not a possible NAI
had taken place, was only estimated
sufficient in 17% of the ER charts.
Conclusions: A majority of the ER charts HD in this
study was insufficient. The physicians
are therefore at risk of missing out on
the opportunity to identify the children
victimized by NAI. In light of the
serious health risks and future
psychosocial consequences, that they
entail, focusing on how to screen NAI
in an ER setting is highly
recommended.
75. Precise and feasible measurements of lateral calcaneal lengthening osteotomies by radiostereometric analysis (RSA)
Polina Martinkevich, Ole Rahbek, Kjeld Søballe, Bjarne Møller-Madsen, Maiken Stilling
Dept. of Children's Orthopaedics, Aarhus University Hospital; Dept. of Orthopedic Surgery, Aarhus University Hospital
Background: RSA is a precise method in measurements
of migration in hip and knee artroplasty and
in assessment of fracture stability.
Lengthening osteotomies of the calcaneus in
children’s orthopaedics are in general
grafted with iliac crest bone. Artificial
structural bone grafts have been introduced.
The durability has not been documented by
RSA.
RSA has not previously been used in clinical
studies of calcaneal osteotomies.
Prior to a clinical study we performed an
RSA study on lateral calcaneal lengthening
osteotomy (LCLO) in cadaver feet.
Purpose / Aim of Study: To determine the feasibility and precision of
marker-based RSA on LCLO with focus on
the osteotomy and the calcaneal-cuboid
(CC) joint.
Materials and Methods: The LCLO was performed in three fixed
adult cadavers (six feet). Tantalum markers
were inserted in the anterior and posterior
fragment of calcaneus and the cuboideum.
Lengthening was done with a plexiglas
wedge. A total of 24 double radiographic
examinations were obtained with the
osteotomy in zero distraction, 1 cm, 1.25 cm
and 1.5 cm distraction to mimic clinical
situations. One foot was excluded from the
study due to loose markers/osteotomy
fracture. Precision was assessed as
systematic bias and 95% repeatability limits.
Findings / Results: Systematic bias was generally below
0.09mm for translations and 1° for rotations.
Precision of LCLO measurements was
below 0.2mm for translations (x,y,z) and
below 3° for rotations. Precision of
migrations measurements in the CC joint
was below 0.4mm for translations and below
2° for rotations about the x,y and z-axes.
Mean condition number for anterior and
posterior calcaneus and the cuboid was
153, 53 and 192.
Conclusions: RSA is a feasible and precise method to
assess migration in LCLO and in the CC
joint, though less precise for rotation.
76. Calcaneal lengthening osteotomy for pes planovalgus using artificial bone graft material. Avoiding donor site morbidity
Martin Gottliebsen, Line Kjeldgaard Pedersen, Ivan Hvid, Michael Davidsen, Ole Rahbek, Bjarne Møller-Madsen
Department of Children`s Orthopaedics, Aarhus University Hospital
Background: Calcaneal lengthening osteotomy can be
used to correct painful pes planovalgus
but it requires the use of graft material to
be inserted as a bone wedge at the
osteotomy site. Obtaining autologous
graft material from the iliac crest in
children is a painful procedure and puts
the child at risk for growth arrest and
iliac wing deformity. New structural bone
graft materials consisting of a mixture of
porous hydroxyapatite (HA) and
tricalcium phosphate (TCP) are being
developed which could prove useful in
paediatric orthopaedic surgery.
Purpose / Aim of Study: We hypothesized that a structural artificial
graft could be used for calcaneal
lengthening osteotomy.
Materials and Methods: A prospective cohort study with ethical
approval was conducted from October 2010
– September 2011. Calcaneal lengthening
was performed in 8 children and
adolescents (9 feet) with mean age 13.1
years (range 6.6-19.2) using wedge shaped
HA/TCP graft material (ReproBone). A cast
was applied for 6-7 weeks after surgery.
Internal fixation of the osteotomy was not
used. Follow up was performed using
radiographs, computed tomography (CT) and
paedobarography.
Findings / Results: Healing of the osteotomy was obtained in all
cases on radiographs and CT images. At
one year follow-up clinical examinations and
paedobarography showed satisfying results
of surgery. No graft failure or wound related
infections were observed.
Conclusions: Harvesting of autologous graft from the iliac
crest may be avoided for calcaneal
lengthening procedures using HA/TCP graft
material. We report satisfying short term
results from a small prospective study with
healing of the osteotomy achieved in all
cases.
77. Effectiveness of reversible total epiphysiodesis using eight-plates. A retrospective clinical study.
Silas Hinsch Gylvin, Martin Gottliebsen, Christian Wong
Orthopaedics, Nordsjællands Hospital; Children's Orthopaedics , Aarhus University Hospital; Children’s Orthopaedics, Hvidovre Hospital
Background: Partial epiphysiodesis using unilateral
eight Plates (EP) is indicated for
correction of angular deformities.
Permanent epiphysiodesis has
traditionally been used for correction of
leg length discrepancy (LLD) ranging
from 2-5 cm. However, it has become
part of clinical practise to perform
temporary growth arrest (GA) by
inserting bilateral EP for correction of
LLD. Only sparse documentation exists
to back up this clinical practise.
Purpose / Aim of Study: To evaluate the results of temporary GA
using bilateral EP technique for correcting
LLD.
Materials and Methods: 14 patients from 2 centers were identified.
All had GA performed using bilateral EP in
femur or femur and tibia. Follow-up data and
radiographs were retrieved and analysed.
Information regarding age at surgery,
gender, comorbidity, complication rate,
amotio atellae and LLD before and during
treatment was registered.
Findings / Results: 14 patients received surgery from 2008
to 2011 with an average age of 13,1
(range 11-15, F=12,M=13,7) at surgery.
Most patients had idiopathic LLD, whilst
clubfoot was the only reoccurring
comorbidity. 10 Patients were operated
on femur alone, and 4 patients on tibia
and femur. They had an average LLD of
2,65cm and 3,75cm, respectively. All had
temporary growth arrest with an average
GA of 1,84cm, with 0,89cm first year,
0,7cm second year and 0,25cm third
year. Average GA for patients operated
on femur alone was 1,98cm, while GA
was 1,5cm on patients with EP in femur
and tibia. 8 patients had implants
removed after mean 29,3 months (range
22-37 months). Boy:girl ratio was 6:4 with
an average GA of 1,94cm and 1,66cm
respectively. The only complication was
postoperative pain, in one case
prolonged.
Conclusions: Bilateral EP seems to be an effective
method to obtain temporary GA and correct
moderate LLD in children with remaining
growth potential.
78. Early experience with a follow-up programme, CPOP for children with Cerebral Palsy.
Kirsten Nordbye-Nielsen, Ole Rahbek, Bjarne Møller-Madsen
Dept. of Children`s Orthopaedics and Orthopaedic Research Laboratory, Aarhus University Hospital; Dept. of Children`s Orthopaedics , Aarhus University Hospital
Background: Children with severe cerebral palsy
(CP) are at risk of secondary
deformities as dislocated hips which
often leads to asymmetry, loss of
mobility, pain and difficulties into daily
activities and personal care. It has
been shown that the Swedish follow-
up programme, CPUP can identify
children at risk of hip dislocation,
leading to early interventions and
prevention of hip dislocation.
Purpose / Aim of Study: To determine the prevalence of
children with hips at risk identified in a
cohort of children between 0-6 years,
with the aim of early intervention and
prevention of hip dislocations.
Materials and Methods: 37 children aged 0-6 years, GMFCS
level I-V. 18 girls and 19 boys have
been included in the follow-up
programme in the Central Region
Denmark from September 2012 until
June 2013. According to the protocol
conventional X-ray of the hips were
obtained. Migration Percentage (MP)
measure was done by the orthopedic
surgeon. Migration Percentage >33
was defined as a hip with dislocation or
in risk for dislocation.
Findings / Results: We analyzed 37 children (74 hips)
GMFCS level I-IV. In the study group
four children were identified with
MP>33,GMFCS level V-IV, two girls
and two boys. Percentage of hips with
MP>33 was 8.1%, 6 of 74 hips.
Conclusions: CPOP seems to be a useful tool
identifying hip pathology at an early
stage leading to early prevention and
interventions by the multidisciplinary
team. Dislocation of hips in cerebral
palsy remains a serious problem and
these data underlines the need of a
national screening programme.
79. 11 years follow-up of congenital hip joint dislocation treated by Ludloffs Approach
Jesper Holbeck-Brendel, Line Kjeldgaard Pedersen, Ole Rahbek, Michel Bach Hellfritzsch , Peter Dalsgaard Nielsen, Bjarne Møller-Madsen
Department of Children’s Orthopedics, Aarhus University Hospital; Department of Radiology, Aarhus University Hospital
Background: Ludloff’s approach for open reduction of
congenital hip joint dislocation first described
in 1908 is commended for its minimal tissue
damage, but is criticized for the risk
(9%-42,9%) of late avascular necrosis
(AVN) of the femoral head.
Purpose / Aim of Study: To evaluate the clinical and radiographic
outcome after treatment of congenital hip
dislocation by Ludloffs approach at the
Department of Children’s Orthopedics,
Aarhus University Hospital.
Materials and Methods: 19 patients underwent Ludloffs approach
from 1997 to 2005 and were invited to follow-
up. 14 children accepted and a clinical and
radiographic examination of the hip and
pelvis were performed. In total 17 hips were
treated with Ludloffs approach. Radiographic
outcome measures were acetabular angle,
migration index (MI) and signs of late
complications in form of both distinct and
subtle signs of AVN. The clinical outcome
measures were range of motion (ROM) of
the hip joints, individual orthopedic
complaints and the HAGOS hip
questionnaire.
Findings / Results: Mean age at surgery was 12 months. Mean
follow-up time was 11,2 years. Radiographic
evaluation showed signs of AVN in 5 of 17
operated hips (29,4%). Six operated hips
have required additional surgery. A
significant correlation was found between
both MI and AVN (p<0,05) and follow-up time
(p<0,01). Difference in ROM for unilateral
treated hips was only significant for flexion
(p<0,02). Two of five questions of quality of
life in the HAGOS hip questionnaire showed
a significant worse outcome for patients with
AVN (p<0,01, p<0,01).
Conclusions: Ludloffs approach is relevant in the
treatment of congenital hip dislocation. This
study indicates an acceptable rate of late
AVN and a general good clinical and
radiographic outcome.
80. Adaptation and Validation of a Danish Translation of CPCHILD© Questionnaire
Peter Buxbom, Derek Curtis, Stig Sonne-Holm, Christian Wong
Orthopedic Department, Hvidovre Hospital; Gait Laboratory, Hvidovre Hospital
Background: No validated questionnaire assessing
health-related quality of life (HRQL) in
children with severe cerebral palsy (CP)
has yet existed. However, the Canadian
CPCHILD questionnaire meets this
deficiency, but has not yet been translated
to Danish.
Purpose / Aim of Study: The purpose of the study was to achieve a
qualitative validated Danish translation of
CPCHILD, in order to be able to assess
quality of life in Danish children with severe
CP and to be able to examine treatment
impact in HRQL and to be able to convey
clinical outcome of treatments
internationally.
Materials and Methods: Bilingual persons performed stepwise
translations, both forward and backward
without looking at the original questionnaire.
The two versions were discussed in the
research group, and summarized to a
temporary Danish translation. Caregivers
of 12 CP children were asked to fill out the
questionnaire and were afterwards
interviewed about any problems or
misunderstandings. The feedback was
discussed in our research group and
incorporated in the final Danish version.
Findings / Results: The CPCHILD questionnaire underwent the
stepwise translation process. The
preliminary Danish version was found easy
understandable by caregivers, and
parental feedback led to only minor
changes. The qualitative Danish translation
can be acquired from the authors.
Conclusions: A qualitative validated Danish version of the
CPCHILD questionnaire is now available.
We are now able to asses HRQL in
children with severe CP (GMFCS IV-V) in
Danish. As soon as a quantitative validation
has been performed we will apply for
making this Danish version of CPCHILD
the official CPCHILD© Project version; this
could best be done on an national basis
due to the large number of ‘patients needed
to treat’.
81. Operative treatment of elbow fractures in pediatric population: Does timing of surgical treatment influence the rate of reoperation and post operative complications?
Pernille Bovbjerg, Zaid Al-Aubaidi
Orthopeadic, Odense University Hospital
Background: Acute surgical procedures are an
integrated part of the daily activity at
any orthopedic department. Some of
these have to be performed in the late
hours of the night.
Purpose / Aim of Study: To analyze the outcome of surgically
treated pediatric elbow fractures. We
expected that the rate of reoperation is
higher for those treated at night.
Materials and Methods: Data collected at a single institution by
searching in the FPAS system using
the ICD and the treatment code. We
had three types of distal humerus
fractures: supracondylar (SC), lateral
condyle (LC) and medial epicondyle
fractures (ME). Surgical timing was
defined as day; 8:00 AM-22:59 PM and
night 23:00 PM- 7:59 AM. Surgeons
were classified into; 1 pediatric
orthopedic surgeon, 2 consultant, 3
specialist, 4 resident and 5 unknown.
Findings / Results: In total 221 patients divided into 158
SC, 35 ME and 28 LC. 43 patients
were operated at night. 10 out of the
43 operations were performed by 1
during the night (23%) and 17 of the 43
by 2 (40%).The remaining 37% are
operated by 3, 4 or 5. At daytime 31%
of the surgeries were performed by 1
and 36% by 2. For 37 SC operated at
night 3 were reoperated (8%), while for
surgery during day time 8 were
reoperated (6.8%). Three elbow
dislocations with ME were operated at
night, but for two patients the fracture
was not identified intraoperatively and
needed extra intervention. For LC
three were operated between 23:00
PM and 7:59 AM and no reoperation.
There was no secondary surgery for
ME and LC operated at day time,
where 9 dislocated elbows were
operated.
Conclusions: This study suggests that patients
operated at the late night time, have
slightly higher reoperation rate.
Generally, surgical procedures should
be performed during the day time,
unless acute intervention is indicated
due to neurovascular comprise.
82. Physeal injuries of the distal humerus – lessons from the Danish Patient Insurance Association.
Andreas Balslev-Clausen, Steffen Volkvardsen, Stig Sonne-Holm, Jens Krogh Christoffersen, Christian Wong
Dept. of Orthopaedic Surgery, Rigshospitalet; Dept. Of Orthopaedic Surgery, Hvidovre University Hospital; , Danish Patient Insurance Association; Dept. of Orthopaedi Surgery, Hviovre University Hospital
Background: Physeal injuries (PI) of the distal humerus
account for 30% of fractures in the distal
humerus. Radiographic diagnosis can be
difficult due to the different ossifications
center and treatment recommendations
are not uniform.
The Danish Patient Insurance Association
(DPIA) decides compensation claims by
patients injured in connection to treatment
by the Danish Health Service
Purpose / Aim of Study: To identify patterns in suboptimal treatment
of PI in the elbow in children.
Materials and Methods: The DPIA database was searched for case
files with PI from 1996 to 2010 for patients 0
to15 years of age. The files were reviewed
with respect to patient characteristics,
treatment and insurance consequences.
Findings / Results: A total of 47 cases were identified. The
boy:girl ratio was 6:4 and with an
average age of 9 years. Distribution of
fractures was 20 medial epicondylar, 3
medial condyle, 4 lateral epicondylar and
18 lateral condyle. Most frequent
complaint was missed fracture at the
initial x-ray (23) with a diagnostic delay
of a median of 29 days. Junior doctors
were responsible for the missed fracture
in 17 cases and 15 of the cases were
medial epicondylar fractures. 5 patients
complained of malpractice due to
insufficient surgery; all performed by
senior doctors. Only two cases had a
range of motion below 100 degrees and
there was no significant varus/valgus
deformity at final case closure. Half of
the injuries were evaluated as a light
injury by the DPI but over 2/3 of the
complaints were acknowledged.
Conclusions: Medial epicondylar fractures are often
missed in the emergency department. In
order to optimize treatment and prevent
doctors delay more awareness - especially
by junior staff - are necessary to avoid
missing these fractures. Radiographs of the
opposite elbow for comparison or review by
an experienced radiologist should be
mandatory.